Johanne Martel-Pelletier

MARTEL-PELLETIER J_sept 2014_4621_ppL

Title: Professor, Department of Medicine, University of Montreal

Head, Chair in Osteoarthritis, University of Montreal

Director, Osteoarthritis Research Unit, University of Montreal

Accredited member, Department of Pharmacology and Physiology,

Faculty of Medicine, University of Montreal

Adress : The Research Centre of the University of Montreal Hospital Centre (CRCHUM)

Tour Viger, Pavillion R, 900 Saint Denis Street

11th Floor, Room, R11-412B

Montreal, Quebec H2X 0A9 Canada

Phone : 514.890.8000 #27281
Email :


  • BSc, Molecular Biology (1973), UQAM
  • Master’s Degree in Physiology (1975), PhD in Physiology (1979), Department of Medicine, University of Montreal
  • Postdoctoral studies, Department of Biophysics, University of Montreal, Montreal, Quebec (1978-1979) and Department of Medicine (Rheumatology), University of Miami, Miami, Florida (1979-1981)

Laboratory research activities

  • Mechanisms underlying the pathophysiology of osteoarthritis
  • Study of new anti-osteoarthritic molecules, ex vivo in humans and in vivoin animal models, and of anti- and pro-catabolic molecules
  • Study of the mechanisms of metalloproteases, of pro- and anti-inflammatory cytokines and of growth factors
  • Study of the pathophysiology of subchondral bone in osteoarthritis
  • Mouse models of OA, knock-out or tissue-specific conditional overexpression
  • Epidemiological and translational studies using cohorts of individuals with osteoarthritis from clinical and/or longitudinal observational studies
  • Development and usages of magnetic resonance imaging systems for articular tissues

Techniques used

  • Molecular and cellular biology
  • Biochemistry
  • Immunology
  • Pharmacology
  • Osteoarthritis animal models
  • Magnetic resonance imaging: reading of articular tissues

Present members

  • Researchers, research assistants, technicians, students (MSc, PhD, post-doctorate)