Publications récentes

Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling. Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP. Mol. Cell. Biol. 2017-04-01;37(7).

High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells. Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, Chagraoui J, Marinier A, Hébert J, Sauvageau G, Kwok BH, Roux PP, Hoang T. J. Clin. Invest. 2016-12-01;126(12):4569-4584.

Myelopoiesis. Lessard JA. and Hoang T. Encyclopedia of Immunobiology 2016-04-27;1:26-37.

SCL/TAL1 in Hematopoiesis and Cellular Reprogramming. Hoang T, Lambert JA, Martin RCurr. Top. Dev. Biol. 2016-02-18;118:163-204.

The LMO2 oncogene regulates DNA replication in hematopoietic cells. Sincennes MC, Humbert M, Grondin B, Lisi V, Veiga DF, Haman A, Cazaux C, Mashtalir N, Affar el B, Verreault A, Hoang T. Proc. Natl. Acad. Sci. U.S.A. 2016-02-02;113(5):1393-8.

Noise-induced effects on multicellular biopacemaker spontaneous activity: Differences between weak and strong pacemaker cells

 Alireza Aghighi and Philippe Comtois

http://aip.scitation.org/doi/10.1063/1.5000809

Septembre 2017

Fitting Local Repolarization Parameters in Cardiac Reaction-Diffusion Models in the Presence of Electrotonic Coupling, A. K. Aswath Kumar, A.

Drahi, V. Jacquemet, Comput. Biol. Med., vol. 81, pp. 55-63, Feb. 2017.

http://dx.doi.org/10.1016/j.compbiomed.2016.12.008

p38 MAPK and the compromised regenerative response of the infarcted adult heart – http://www.smartscitech.com/index.php/crm

Cardiovascular Regenerative Medicine 2017; 4: e1508. doi: 10.14800/crm.1508; © 2017 by Angelino Calderone

Nouvel ouvrage du Dr Pierre Beaulieu aux Presses de l’Université de Montréal

La douleur – Guide pharmacologique et thérapeutique – 2e édition (2015)

la-douleur

Pour en savoir plus

mars 2014

Précis de pharmacologie

precis

Nous tenons à féliciter les Drs Pierre Beaulieu et Chantal Lambert, professeurs au Département de pharmacologie et physiologie pour leur plus récente publication : Précis de Pharmacologie.
Bien que multi-auteurs, ce précis est écrit pratiquement en totalité par des enseignants, chercheurs, cliniciens, doctorants appartenant ou ayant appartenu à l’UdeM et à McGill, ce qui en fait un ouvrage montréalais, québécois et francophone unique. Le but des auteurs est d’offrir un ouvrage en langue française, clair, précis et didactique de ce qu’est la pharmacologie aujourd’hui.

L’ouvrage est divisé en 37 chapitres regroupés en sept sections. Les sept premiers chapitres présentent les bases fondamentales de la pharmacologie, les sections suivantes couvrent l’ensemble de la pharmacologie par systèmes.
Le Précis de Pharmacologie s’adresse à l’ensemble de la communauté étudiante en sciences de la santé ainsi qu’aux divers professionnels qui voudraient acquérir ou réviser leurs connaissances dans le domaine.


Pour commander

Najmanovich RJ. Evolutionary studies of ligand binding sites in proteins. Curr Opin Struct Biol. 2017;45: 85–90. doi:10.1016/j.sbi.2016.11.024 http://dx.doi.org/10.1016/j.sbi.2016.11.024

Frappier V, Chartier M, Najmanovich R. Applications of Normal Mode Analysis Methods in Computational Protein Design. Methods Mol Biol. 2017;1529: 203–214. doi:10.1007/978-1-4939-6637-0_9 http://dx.doi.org/10.1007/978-1-4939-6637-0_9

High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells. Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, Chagraoui J, Marinier A, Hébert J, Sauvageau G, Kwok BH, Roux PP, Hoang T. J. Clin. Invest. 2016-12-01;126(12):4569-4584.

Myelopoiesis. Lessard JA. and Hoang T. Encyclopedia of Immunobiology 2016-04-27;1:26-37.

SCL/TAL1 in Hematopoiesis and Cellular Reprogramming. Hoang T, Lambert JA, Martin RCurr. Top. Dev. Biol. 2016-02-18;118:163-204.

The LMO2 oncogene regulates DNA replication in hematopoietic cells. Sincennes MC, Humbert M, Grondin B, Lisi V, Veiga DF, Haman A, Cazaux C, Mashtalir N, Affar el B, Verreault A, Hoang T. Proc. Natl. Acad. Sci. U.S.A. 2016-02-02;113(5):1393-8.

Siamak Salavatian, Eric Beaumont, Jean-Philippe Longpré, John Armour, Alain Vinet, Vincent Jacquemet, Kalyanam Shivkumar, and Jeffrey Ardell.  Vagal stimulation targets select populations of intrinsic cardiac neurons to control neurally-induced atrial fibrillation. AJP-Heart and Circulatory Physiology, doi: 10.1152/ajpheart.00443.2016, 2016

Chabot A, Hertig V, Boscher E, Nguyen QT, Boivin B, Chebli J, Bissonnette E, Villeneuve L, Brochiero E, Dupuis J, Calderone A.  Endothelial and Epithelial Cell Transition to a Mesenchymal Phenotype Was Delineated by Nestin Expression.  J Cellular Physiology 2016 Jul;231(7):1601-10. (Highlighted paper; Featured on the Front Cover; J Cellular Physiology 2016 Jul;231(7):i. doi: 10.1002/jcp.25377).

Meus MA, Hertig V, Villeneuve L, Jasmin J-F, Calderone A. Nestin expression by pre-existing cardiomyocytes recapitulated in part an embryonic phenotype; suppressive role of p38 MAPK. J Cell Physiol. 2016 Jul 20. doi: 10.1002/jcp.25496. (Epub ahead of print).

Gagnon D, Romero SA, Cramer MN, Jay O, Crandall CG (2016). Cardiac and Thermal Strain of Elderly Adults Exposed to Extreme Heat and Humidity With and Without Electric Fan Use. JAMA. 316(9): 989-991.

Gagnon D, Romero SA, Ngo H, Sarma S, Cornwell WK 3rd, Poh PY, Stoller D, Levine BD, Crandall CG. (2016). Healthy aging does not compromise the augmentation of cardiac function during heat stress. J Appl Physiol. 121(4): 885-892.

Gagnon D, Romero SA, Ngo H, Poh PY, Crandall CG (2016). Plasma hyperosmolality attenuates skin sympathetic nerve activity during passive heat stress in humans. J Physiol. 594(2): 497-506.

Gagnon D, Schlader ZJ, Adams A, Rivas E, Mulligan J, Grudic GZ, Convertino VA, Howard JT, Crandall CG (2016). The Effect of Passive Heat Stress and Exercise-Induced Dehydration on the Compensatory Reserve During Simulated Hemorrhage. Shock. 46 (3 suppl 1) : 74-82.

Vagal Stimulation Targets Select Populations of Intrinsic Cardiac Neurons to Moderate Neurally-Induced Atrial Fibrillation, S. Salavatian, E. Beaumont, J. P. Longpré, J. A. Armour, A. Vinet, V. Jacquemet, K. Shivkumar, J. L. Ardell, Am. J. Physiol. Heart Circ. Physiol., Sep. 2016 (DOI:10.1152/ajpheart.00443.2016).

Lessons from Computer Simulations of Ablation of Atrial Fibrillation, V. Jacquemet, J. Physiol., vol. 594, pp. 2417-2430, Mar. 2016.

Remote Ischemic Preconditioning Shortens QT Intervals During Exercise in Healthy Subjects, M. Caru, F. Lalonde, H. Gravel, C. Daigle, F. Tournoux, V. Jacquemet, D. Curnier, Eur. J. Sport Sci., vol. 16, no. 8, pp. 1005-1013, Feb. 2016.

A Simple Analytical Model of Action Potential Duration Profile in Electrotonically-Coupled Cells, V. Jacquemet, Math. Biosci., vol. 272, pp. 92-99, Feb. 2016.

Klein H, A. Abu-Arish, NT Trinh, Y Luo, PW Wiseman, JW Hanrahan , E. Brochiero, R. Sauvé. (2016) Investigating CFTR and KCa3.1 Protein/Protein Interactions. PLoS One. Apr 19;11(4):e0153665

Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling. Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP. Mol. Cell. Biol. 2017-04-01;37(7).

High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells. Gerby B, Veiga DF, Krosl J, Nourreddine S, Ouellette J, Haman A, Lavoie G, Fares I, Tremblay M, Litalien V, Ottoni E, Kosic M, Geoffrion D, Ryan J, Maddox PS, Chagraoui J, Marinier A, Hébert J, Sauvageau G, Kwok BH, Roux PP, Hoang T. J. Clin. Invest. 2016-12-01;126(12):4569-4584.

Myelopoiesis. Lessard JA. and Hoang T. Encyclopedia of Immunobiology 2016-04-27;1:26-37.

SCL/TAL1 in Hematopoiesis and Cellular Reprogramming. Hoang T, Lambert JA, Martin RCurr. Top. Dev. Biol. 2016-02-18;118:163-204.

The LMO2 oncogene regulates DNA replication in hematopoietic cells. Sincennes MC, Humbert M, Grondin B, Lisi V, Veiga DF, Haman A, Cazaux C, Mashtalir N, Affar el B, Verreault A, Hoang T. Proc. Natl. Acad. Sci. U.S.A. 2016-02-02;113(5):1393-8.