Publications récentes

Periostin, a signal transduction intermediate in TGF-β-induced EMT in U-87MG human glioblastoma cells, and its inhibition by anthocyanidins.
Ouanouki A, Lamy S, Annabi B. (2018)
Oncotarget, 2018, 9 (31):22023-22037

Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
Chennupati V, Veiga DF, Maslowski KM, Andina N, Tardivel A, Yu EC, Stilinovic M, Simillion C, Duchosal MA, Quadroni M, Roberts I, Sankaran VG, MacDonald HR, Fasel N, Angelillo-Scherrer A, Schneider P, Hoang T, Allam R.
J Clin Invest. 2018 Apr 2;128(4):1597-1614. doi: 10.1172/JCI94956. Epub 2018 Mar 19.
PMID: 29408805

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Smith MJ, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M. Nat Commun. 2017 Oct 23;8(1):1099. doi: 10.1038/s41467-017-01326-5.
PMID: 29062045

Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.
Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP.
Mol Cell Biol. 2017 Mar 17;37(7). pii: e00357-16. doi: 10.1128/MCB.00357-16. Print 2017 Apr 1.
PMID: 28096188

The tyrosine phosphatase STEP is involved in age-related memory decline.
Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn A, Norris CM, Ferland G, Bézard E, Gaudreaud P, Lombroso P & Brouillette J (2018)
Current Biology; 28(7): 1079-1089

A three-way inter-molecular network accounts for the CaVα2δ1-induced functional modulation of the pore-forming CaV1.2 subunit.
Briot J, Mailhot O, Bourdin B, Tétreault MP, Najmanovich R, Parent L.
J Biol Chem. 2018 Mar 27. pii: jbc.RA118.001902. doi: 10.1074/jbc.RA118.001902.

Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors.
Djerir D, Iddir M, Bourgault S, Lamy S, ANNABI B (2018)
Biophysical Chemistry 234:34–41

High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats.
Allain F, Bouayad-Gervais K, Samaha AN.
Psychopharmacology (Berl). 2018 Jan;235(1):317-328. doi: 10.1007/s00213-017-4773-8. Epub 2017 Oct 31.
PMID: 29085961

Analgésie. In Anesthésie-réanimation en chirurgie thoracique
Garneau S, Girard F, Beaulieu P.
Edit. Bussière J & Léone M. Arnette, 2017; p. 421-440. ISBN 10 : 2718413832.

The addicted patient. In Anesthesia in High-Risk Patients.
Beaulieu P.
Eds. Fellahi JL & Leone M. Springer, 2017; p. 317-339. ISBN 978-3-319-60804-4 (eBook)

Expression, distribution and function of kinin B1 receptor in the rat diabetic retina.
Hachana S, Bhat M, Sénécal J, Huppé-Gourgues F, Couture R, Vaucher E.
Br J Pharmacol. 2017 Dec 29. doi: 10.1111/bph.14138. [Epub ahead of print]
PMID: 29285756

Population Pharmacokinetics of Trimethoprim-Sulfamethoxazole in Infants and Children.
Autmizguine J, Melloni C, Hornik CP, Dallefeld S, Harper B, Yogev R, Sullivan JE, Atz AM, Al-Uzri A, Mendley S, Poindexter B, Mitchell J, Lewandowski A, Delmore P, Cohen-Wolkowiez M, Gonzalez D; the Pediatric Trials Network Steering Committee.
Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01813-17. doi: 10.1128/AAC.01813-17. Print 2018 Jan.

Chitosan-doxycycline hydrogel: An MMP inhibitor/sclerosing embolizing agent as a new approach to endoleak prevention and treatment after endovascular aneurysm repair.
Zehtabi F, Ispas-Szabo P, Djerir D, Sivakumaran L, Annabi B, Soulez G, Mateescu MA, Lerouge S.
Acta Biomater. 2017 Dec;64:94-105. doi: 10.1016/j.actbio.2017.09.021. Epub 2017 Sep 18.
PMID: 28927932

Anesthesia for patients on recreational drugs.
Beaulieu P.
Canadian Journal of Anesthesia 2017; 64(12): 1236-64.

Primary Role for Kinin B1 and B2 Receptors in Glioma Proliferation.
Nicoletti NF, Sénécal J, da Silva VD, Roxo MR, Ferreira NP, de Morais RLT, Pesquero JB, Campos MM, Couture R, Morrone FB.
Mol Neurobiol. 2017 Dec;54(10):7869-7882. doi: 10.1007/s12035-016-0265-9. Epub 2016 Nov 16.
PMID: 27848207

Dynamic SERS nanosensor for neurotransmitter sensing near neurons.
Lussier F, Brulé T, Bourque MJ, Ducrot C, Trudeau LÉ, Masson JF.
Faraday Discuss. 2017 Dec 4;205:387-407. doi: 10.1039/c7fd00131b.
PMID: 28895964

Posaconazole Plasma Monitoring in Immunocompromised Children.
McMahon J, Théorêt Y, Autmizguine J, Bittencourt H, Tapiéro B, Ovetchkine P.
J Pediatric Infect Dis Soc. 2017 Nov 24;6(4):389-392. doi: 10.1093/jpids/piw087.

Argan Oil as an Effective Nutri-Therapeutic Agent in Metabolic Syndrome: A Preclinical Study.
El Midaoui A, Haddad Y, Filali-Zegzouti Y, Couture R.
Int J Mol Sci. 2017 Nov 22;18(11). pii: E2492. doi: 10.3390/ijms18112492.
PMID: 29165388

Localization and Interaction between Kinin B1 Receptor and NADPH Oxidase in the Vascular System of Diabetic Rats.
Haddad Y, Couture R.
Front Physiol. 2017 Oct 31;8:861. doi: 10.3389/fphys.2017.00861. eCollection 2017.
PMID: 29163205

Theoretical and Experimental Comparison of Lag-Based and Time-Based Exponential Moving Average Models of QT Hysteresis.
V. Jacquemet, H. Gravel, D. Curnier, A. Vinet
Physiol. Meas., vol. 38, no. 10, pp.1885-1905, Oct. 2017.


Negatively charged residues in the first extracellular loop of the L-type CaV1.2 channel anchor the interaction with the CaVα2δ1 auxiliary subunit.
Bourdin B, Briot J, Tétreault MP, Sauvé R, Parent L.
J Biol Chem. 2017 Oct 20;292(42):17236-17249. doi: 10.1074/jbc.M117.806893. Epub 2017 Sep 1.

Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism.
Gleave JA, Arathoon LR, Trinh D, Lizal KE, Giguère N, Barber JHM, Najarali Z, Khan MH, Thiele SL, Semmen MS, Koprich JB, Brotchie JM, Eubanks JH, Trudeau LE, Nash JE.
Neurobiol Dis. 2017 Oct;106:133-146. doi: 10.1016/j.nbd.2017.06.009. Epub 2017 Jul 1.
PMID: 28673739

A Statistical Model of False Negative and False Positive Detection of Phase Singularities.
V. Jacquemet
Chaos, vol. 27, no. 10, pp. 103124, Oct. 2017.

DNA methylation targeted drugs.
Elodie M. Da Costa, Gabrielle McInnes, Annie Beaudry, and Noël J.-M. Raynal.
The Cancer Journal: The Journal of Principles & Practice of Oncology, 2017 Sep/Oct;23(5):270-276

Oleic Acid in the Ventral Tegmental Area Inhibits Feeding, Food Reward, and Dopamine Tone.
Hryhorczuk C, Sheng Z, Décarie-Spain L, Giguère N, Ducrot C, Trudeau LÉ, Routh VH, Alquier T, Fulton S.
Neuropsychopharmacology. 2017 Sep 27. doi: 10.1038/npp.2017.203. [Epub ahead of print]
PMID: 28857071

Noise-induced effects on multicellular biopacemaker spontaneous activity: Differences between weak and strong pacemaker cells
A. Aghighi and P. Comtois
Chaos, vol. 27, no 9, pp. 093927, Sept 2017.

Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment
Servonnet A, Minogianis EA, Bouchard C, Bédard AM, Lévesque D, Rompré PP, Samaha AN.
Neuropharmacology. 2017 Sep 1;123:10-21. doi: 10.1016/j.neuropharm.2017.05.015. Epub 2017 May 15.
PMID: 28522313

Cavin-2 Functions as a Suppressive Regulator in TNF-induced Mesenchymal Stromal Cell Inflammation and Angiogenic Phenotypes.
Annabi B, Zgheib A, Annabi B.
Int J Stem Cells. 2017 May 30;10(1):103-113. doi: 10.15283/ijsc16032.
PMID: 28024316


Cardiac Contractility: Correction Strategies Applied to Telemetry Data from a HESI-Sponsored Consortium
E. Boulay, M. V. Accardi, H. Huang, V. Jacquemet, A. Vinet, A. Ascah, M. K. Pugsley, M. Soloviev, E. Troncy, J. M. Doyle, J. B. Pierson, S. Authier, J.
Pharmacol. Toxicol. Methods, vol. 87, pp. 38-47, Sept. 2017.

Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia.
Schroeder T, Piantadosi CA, Natoli MJ, Autmizguine J, Cohen-Wolkowieczs M, Hamilton KL, Bell C, Klawitter J, Christians U, Irwin DC, Noveck RJ.
Clin Pharmacol Ther. 2017 Aug 31. doi: 10.1002/cpt.860. [Epub ahead of print]

Dose-Exposure Simulation for Piperacillin-Tazobactam Dosing Strategies in Infants and Young Children.
Thibault C, Kassir N, Théorêt Y, Varin F, Litalien C, Autmizguine J.
J Popul Ther Clin Pharmacol. 2017 Aug 21;24(3):e33-344. doi: 10.22374/1710-6222.

Kininase 1 As a Preclinical Therapeutic Target for Kinin B1 Receptor in Insulin Resistance.
Haddad Y, Couture R.
Front Pharmacol. 2017 Aug 2;8:509. doi: 10.3389/fphar.2017.00509. eCollection 2017.
PMID: 28824433

Impact of pioglitazone and bradykinin type 1 receptor antagonist on type 2 diabetes in high-fat diet-fed C57BL/6J mice.
El Akoum S, Haddad Y, Couture R.
Obes Sci Pract. 2017 Jul 6;3(3):352-362. doi: 10.1002/osp4.117. eCollection 2017 Sep.
PMID: 29071111

Proteolytic cleavage of the hydrophobic domain in the CaVα2δ1 subunit improves assembly and activity of cardiac CaV1.2 channels.
Segura E, Bourdin B, Tétreault MP, Briot J, Allen BG, Mayer G, Parent L.
J Biol Chem. 2017 Jun 30;292(26):11109-11124. doi: 10.1074/jbc.M117.784355. Epub 2017 May 11.

A Transcriptional Regulatory Role for the Membrane Type-1 Matrix Metalloproteinase in Carcinogen-Induced Inflammasome Gene Expression.
Sheehy S, Annabi B.
Gene Regul Syst Bio. 2017 Jun 8;11:1177625017713996. doi: 10.1177/1177625017713996. eCollection 2017.
PMID: 28634425

Antipsychotic-Induced Dopamine Supersensitivity Psychosis: Pharmacology, Criteria, and Therapy.
Chouinard G, Samaha AN, Chouinard VA, Peretti CS, Kanahara N, Takase M, Iyo M.
Psychother Psychosom. 2017;86(4):189-219. doi: 10.1159/000477313. Epub 2017 Jun 24.
PMID: 28647739

Cerebrovascular Angiogenic Reprogramming upon LRP1 Repression: Impact on Sphingosine-1-Phosphate-Mediated Signaling in Brain Endothelial Cell Chemotactism.
Vézina A, Charfi C, Zgheib A, Annabi B.
Mol Neurobiol. 2017 May 17. doi: 10.1007/s12035-017-0614-3. [Epub ahead of print]
PMID: 28516428

Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling. Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP.
Mol. Cell. Biol. 2017-04-01;37(7)


Characterization of a Human Point Mutation of VGLUT3 (p.A211V) in the Rodent Brain Suggests a Nonuniform Distribution of the Transporter in Synaptic Vesicles.
Ramet L, Zimmermann J, Bersot T, Poirel O, De Gois S, Silm K, Sakae DY, Mansouri-Guilani N, Bourque MJ, Trudeau LE, Pietrancosta N, Daumas S, Bernard V, Rosenmund C, El Mestikawy S.
J Neurosci. 2017 Apr 12;37(15):4181-4199. doi: 10.1523/JNEUROSCI.0282-16.2017. Epub 2017 Mar 17.
PMID: 28314816

Inherited Ventricular Arrhythmias: The Role of the Multi-Subunit Structure of the L-Type Calcium Channel Complex.
Briot J, Tétreault MP, Bourdin B, Parent L.
Adv Exp Med Biol. 2017;966:55-64. doi: 10.1007/5584_2016_186.

Anthocyanidins inhibit epithelial-mesenchymal transition through a TGFβ/Smad2 signaling pathway in glioblastoma cells.
Ouanouki A, Lamy S, Annabi B.
Mol Carcinog. 2017 Mar;56(3):1088-1099. doi: 10.1002/mc.22575. Epub 2016 Oct 4.
PMID: 27649384

Fitting Local Repolarization Parameters in Cardiac Reaction-Diffusion Models in the Presence of Electrotonic Coupling
A. K. Aswath Kumar, A. Drahi, V. Jacquemet
Comput. Biol. Med., vol. 81, pp. 55-63, Feb. 2017.

Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome.
Noël J-M Raynal, Elodie DA COSTA, Justin Lee, Gabriel Malouf, Sarah Dumont, Vazganush Gharibyan, Saira Ahmed, and Jean-Pierre J. Issa.
Molecular Cancer Therapeutics, February 1 2017 16 (2) 397-407.

p38 MAPK and the compromised regenerative response of the infarcted adult heart
A. Calderone
Cardiovascular Regenerative Medicine 2017; 4: e1508. doi: 10.14800/crm.1508; © 2017

Inherited Ventricular Arrhythmias: The Role of the Multi-Subunit Structure of the L-Type Calcium Channel Complex
Briot J, Tétreault MP, Bourdin B, Parent L.
Adv Exp Med Biol. 2017;966:55-64. doi: 10.1007/5584_2016_186.