Title: | Professor, Department of Medicine, University of Montreal
Head, Chair in Osteoarthritis, University of Montreal Director, Osteoarthritis Research Unit, University of Montreal Accredited member, Department of Pharmacology and Physiology, Faculty of Medicine, University of Montreal |
Adress : | The Research Centre of the University of Montreal Hospital Centre (CRCHUM)
Tour Viger, Pavillion R, 900 Saint Denis Street 11th Floor, Room, R11-412B Montreal, Quebec H2X 0A9 Canada |
Phone : | 514.890.8000 #27281 |
Email : | jm@martelpelletier.ca |
Formation
- BSc, Molecular Biology (1973), UQAM
- Master’s Degree in Physiology (1975), PhD in Physiology (1979), Department of Medicine, University of Montreal
- Postdoctoral studies, Department of Biophysics, University of Montreal, Montreal, Quebec (1978-1979) and Department of Medicine (Rheumatology), University of Miami, Miami, Florida (1979-1981)
Laboratory research activities
- Mechanisms underlying the pathophysiology of osteoarthritis
- Study of new anti-osteoarthritic molecules, ex vivo in humans and in vivoin animal models, and of anti- and pro-catabolic molecules
- Study of the mechanisms of metalloproteases, of pro- and anti-inflammatory cytokines and of growth factors
- Study of the pathophysiology of subchondral bone in osteoarthritis
- Mouse models of OA, knock-out or tissue-specific conditional overexpression
- Epidemiological and translational studies using cohorts of individuals with osteoarthritis from clinical and/or longitudinal observational studies
- Development and usages of magnetic resonance imaging systems for articular tissues
Techniques used
- Molecular and cellular biology
- Biochemistry
- Immunology
- Pharmacology
- Osteoarthritis animal models
- Magnetic resonance imaging: reading of articular tissues
Present members
- Researchers, research assistants, technicians, students (MSc, PhD, post-doctorate)
Publications
http://www.ncbi.nlm.nih.gov/pubmed/?term=Martel-Pelletier+J%5Bau%5D