Sergio Crespo-Garcia

Sciences de la santéSciences médicalesSciences naturelles et génie
Professeur adjoint
École d'optométrie
Pavillon 3744, rue Jean-Brillant, local 230-35
514 343-6111, poste 13652
Professeur accrédité
Faculté de médecine - Département de pharmacologie et physiologie

Disciplines

  • Optométrie
  • Ophtalmologie
  • Biologie cellulaire

Présence sur le Web

Expertise de recherche

Sergio Crespo-Garcia effectue des recherches dans le domaine de la dégénérescence rétinienne et du diabète. Ses intérêts de recherche sont de mieux comprendre les interactions entre les différentes cellules aux vaisseaux sanguins dans la rétine atteinte d’une maladie oculaire.

Affiliations de recherche UdeM

Titres professionnels et autres affiliations

Canada Coordinator - Marie Curie Alumni Association North-America Chapter

Formations

2022 - Post-doctorate - Biochimie médicale
Centre de recherche Hôpital Maisonneuve-Rosemont (Canada)
2017 - Dr. rer. med. - Sciences biomédicales
Charité Universitätsmedizin Berlin (Allemagne)
2016 - Post-graduate certificate - Ophtalmologie
University of Lincoln (Royaume-Uni)
2013 - M.Sc. - Biologie cellulaire
Universidad Complutense de Madrid (Espagne)
2012 - B.Sc. - Biologie et autres sciences connexes
IE University (Espagne)

Pour en savoir plus

Prix et distinctions

2022: HMR Foundation Publication Prize on Cell Metabolism 2021 (Canada)

2021: Montreal Diabetes Research Center Postdoctoral Award (Canada)

2021: Association for Research in Vision and Ophthalmology (ARVO) Travel Award (USA)

2021: Publication Prize Relève Étoile Jacqes-Genest on Cell Metabolism 2021 (Canada)

2021: Publication Prize Réseau Vision on Cell Metabolism 2021 (Canada)

2018-2021: Fonds de Recherche du Québec - Santé (FRQ-S) Postdoctoral Scholarship (Canada)

2018-2019: Hospital Maisonneuve-Rosemont (HMR) Foundation Postdoctoral Scholarship (Canada)

2017: Dr. Margot Engelmann Foundation Doctorate Award (Germany)

2016: International Society for Eye Research (ISER) Travel Award (Japan)

2013-2016: Marie Curie ITN Early Stage Researcher Scholarship (Germany)

2012-2013: “la Caixa” Foundation Masters Scholarship (Spain)

2012: IE University Promotion 2008 Valedictorian (Spain)

2012: IE University First Grade Honors Distinction (First-of-the-class) (Spain)

2011-2012: Spanish Ministry of Education Beca de Colaboración - Research Scholarship (Spain)

2010-2012: IE University Academic Excellence Scholarship (Spain)

2009-2010: IE University Honors Scholarship (Spain)

Publications

Crespo-Garcia S, Tsuruda PR, Dejda A, Ryan RD, Fournier F, ..., Dubrac A, Beausejour C, Armstrong S, Mallette FA, Yohn CB, Joyal JS, Marquess D, Beltran PJ, Sapieha P. 2021. Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination through BCL-xL inhibition. Cell Metabolism. Apr 6;33(4):818-832.e7

Crespo-Garcia S, Reichhart N, Skosyrski S, Kociok N, Joussen AM. 2021.Anti-inflammatory role of netrin-4 in diabetic retinopathy. Int. Journal Molecular Sciences. Apr 25;22(9):4481

Binet F, Cagnone G, Crespo-Garcia S, Hata M, Neault M, Dejda A, Wilson AM, Buscarlet M, ..., Côté JF, Andelfinger G, Rezende FA, Sennlaub F, Joyal J-S, Mallette FA, Sapieha P. 2020. Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy. Science. Aug 21;369(6506):eaay5356

Crespo-Garcia S, Reichhart N, Wigdahl J, Skosyrski S, Kociok N, Strauß, Joussen AM. 2019. Lack of netrin-4 alters vascular remodeling in the retina. Graefes Arch Clin Exp Ophthalmol. 257: 2179–2184.

Crespo-Garcia S, Reichhart N, Skosyrski S, Mr. Foddis M, Wu J, ..., Sassi C, Dirnagl U, Joussen AM, Strauss O. 2018. Individual and temporal variability of the retina after chronic bilateral common carotid artery occlusion (BCCAO). PloS One. 13(3)

Crespo-Garcia S, Corkhill C, Roubeix C, Davids AM, Kociok N, Strauss O, Joussen AM, Reichhart N. 2017. Inhibition of placenta growth factor reduces subretinal mononuclear phagocyte accumulation in choroidal neovascularization, Investig. Ophthalmol. Vis. Sci. 58(12): 4997-5006.

Reichhart N*, Crespo-Garcia S*, Haase N, Golic M, Skosyrski S, Rübsam A, ..., Bader M, Dechend R, Strauss O, Joussen AM. 2016. TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knock-down, Diabetologia. 60(1):202-211 *First author

Kociok N *, Crespo-Garcia S*, Liang Y, Klein SV, Nürnberg C, Reichhart N, Skosyrski S, Moritz E, Maier AK, Brunken WJ, Strauss O, Koch M, Joussen AM. 2016. Lack of netrin-4 modulates pathologic neovascularization in the eye, Scientific Reports. 6:18828 *First author

Crespo-Garcia S, Reichhart N, Hernandez-Matas C, Zabulis X, Kociok N, Brockmann C, Joussen AM, Strauss O. 2015. In vivo analysis of the time and spatial activation pattern of microglia in the retina following laser-induced choroidal neovascularization. Experimental Eye Research. 139, 13-21