Jean-Philippe Lafrance

Formation

• MD, Université de Montréal (2001).
• Collège Royal de Médecine interne (FRCPC) (2005).
• Certificat en Néphrologie (CSPQ et FRCPC)(2006).
• MSc en épidémiologie, Université McGill (2009).
• Post-doctorat en phamacoépidémiologie, Université de Boston (2009)

Thèmes de recherche

• Effets secondaires rénaux tels que l’insuffisance rénale aiguë suite à l’utilisation de médicaments largement utilisés dans la population générale (exemple : anti-inflammatoires non-stéroidiens).
• Utilisation et effets secondaires des médicaments chez les patients souffrant de maladie rénale chronique ou nécessitant la dialyse.
• Épidémiologie et facteurs de risque des complications infectieuses chez les patients souffrant d’insuffisance rénale terminale.
• Incidence, facteurs de risque et conséquences reliés à l’insuffisance rénale aiguë chez les patients atteints d’insuffisance rénale chronique.

Membres du laboratoire

• Naoual Elftouh, MSc, analyste-statisticienne
• Noor Alsalemi, étudiante au Ph.D.

Publications

• Tseng CL, Rajan M, Miller DR, Lafrance JP, Pogach L. Trends in initial lower extremity amputation rates among Veterans Health Administration Health Care System Users from 2000 to 2004. Diabetes Care 2011: [epub ahead of print]

• Rahme E, Roussy JP, Lafrance JP, Nedjar H, Morin S. Utilisation of non-steroidal anti-inflammatory drugs: Is there a change in the patient risk profile after the withdrawal of rofecoxib? J Rheumatology. 2010: [epub ahead of print].

• Williams LH, Miller DR, Fincke G, Lafrance JP, Etzioni R, Maynard C, Raugi GJ, Reiber GE. Depression and incident lower limb amputations in veterans with diabetes. J Diabetes Complications. 2010: [epub ahead of print].

• Lafrance JP, Miller DR. Defining acute kidney injury in database studies, varying baseline kidney function assessment period and chronic kidney disease status. Am J Kidney Dis. 2010; 56(4):651-660.

• Lafrance JP, Djurdjev O, Levin A. Incidence and Outcomes of Acute Kidney Injury in a Referred Chronic Kidney Disease Cohort. Nephrol Dial Transplant. 2010; 25(7):2203-2209.

• Lafrance JP, Miller DR. Acute Kidney Injury Associates with Long-Term Mortality. J Am Soc Nephrol. 2010; 21(2):345-352.

• Lafrance JP, Iqbal S, Lelorier J, Dasgupta K, Ritchie J, Ward L, Benaroya S, Barré P, Cantarovich M, Ghannoum M, Proulx N, Vasilevsky M, Rahme E. Vascular Access-Related Bloodstream Infections in First Nations, Community and Teaching Canadian Dialysis Units, and Other Centre-Level Predictors. Nephron Clin Pract. 2010; 114(3):c204-212.

• Lafrance JP, Miller D. Selective and Non-Selective Non-Steroidal Anti-Inflammatory Drugs and the Risk of Hospitalization with Acute Kidney Injury. Pharmacoepidemiol Drug Saf. 2009;18(10): 923-31.

• Rahme E, Lafrance JP, Nedjar H, Rahme G, Morin S. Discrepancy among observational studies: example of naproxen-associated adverse events. Open Rheumathology J. 2008;3: 1-8.

• Bouchard J, Ouimet D, Vallé M, Lafrance JP, Leblanc M, Senécal L, Bonnardeaux A, Mathieu J, Pichette V. Comparison of the prevalence of calcidiol insufficiency in predialysis and osteoporotic populations. Int Urol Nephrol. 2008. [Epub ahead of print].

• Lafrance JP, Rahme E, Lelorier J, Iqbal S. Vascular Access-Related Infections: Definitions, Incidence Rates and Risk Factors. Am J Kidney Dis. 2008; 52(5): 982-93.

• Michaud J, Nolin T, Naud J, Lafrance JP, Leblond F, Himmelfarb J, Pichette V. Effect of Hemodialysis on Hepatic Cytochrome P450 Functional Expression. J Pharmacol Sci.2008; 108(2): 157-63.

• Lafrance JP, Letourneau I, Ouimet D, Bonnardeaux A, Leblanc M, Mathieu N, Pichette V. Successful treatment of encapsulating peritoneal sclerosis with immunosuppressive therapy. Am J Kidney Dis. Feb 2008;51(2):e7-10.

• Leblanc M, Lafrance JP, Renald A. Dialyzer fiber bundle volume during hemodialysis using large-surface dialyzers. ASAIO J. Nov-Dec 2006;52(6):646-651.

• Lafrance JP, Madore F, Querin S. Lactococcus cremoris Peritonitis in a CAPD Patient.Perit Dial Int. Nov-Dec 2006;26(6):716-717.

• Robitaille R, Lafrance JP, Leblanc M. Altered laboratory findings associated with end-stage renal disease. Semin Dial. 2006; 19(5):373-380.

• Lafrance JP, Leblanc M. Intestinal Manifestations With A Surface-Treated AN69 Membrane And ACEI During Hemodialysis. Nephrol Dial Transplant. 2006 ;21(10):2999-3000.

• Lafrance JP, Nolin L, Senécal L, Leblanc M. Predictors and outcome of cardiopulmonary resuscitation (CPR) calls in a large haemodialysis unit over a seven-year period. Nephrol Dial Transplant. 2006; 21:1006-1012.