| Titre: |
Professeur titulaire |
| Adresse: | Institut de Cardiologie de Montréal 5000 Est, rue Bélanger Montréal (Québec) H1T 1C8 |
| Local: | S-3320 |
| Téléphone: | 514 376-3330, poste 3170 |
| Courriel: | angelo.calderone@umontreal.ca |
Formation
- B.Sc. Biochimie , McGill University (1986)
- Ph.D. Physiologie , Université de Montréal, (1992)
- Stage post-doctoral, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA (1995)
Thèmes de recherche
- Remodelage et Régénération Cardiaque
Approches techniques
- Modèles de rat/souris de l’infarctus myocarde, pression surcharge, diabète type I et transplantation cellulaire.
- Culture cellulaire des cardiomyocytes des rats nouveau-nés, les fibroblastes ventriculaires et les cellules muscle lisse vasculaire.
- Immunofluorescence, lentivirus, adénovirus, Western.
Membre du laboratoire
- À venir
Publications
Hertig V, Matos-Nieves A, Garg V, Villeneuve L, Mamarbachi M, Caland L, Calderone A. Nestin expression is dynamically regulated in cardiomyocytes during embryogenesis. J Cell Physiol. 2018 Apr;233(4):3218-3229. doi: 10.1002/jcp.26165. Epub 2017 Sep 27.
Calderone A. The Biological Role of Nestin(+)-Cells in Physiological and Pathological Cardiovascular Remodeling. Front Cell Dev Biol. 2018 Feb 14;6:15. doi: 10.3389/fcell.2018.00015. eCollection 2018.
Meus MA, Hertig V, Villeneuve L, Jasmin J-F, Calderone A. Nestin expression by pre-existing cardiomyocytes recapitulated in part an embryonic phenotype; suppressive role of p38 MAPK. J Cellular Physiology. 2017 Jul;232(7):1717-1727
Calderone A. p38 MAPK and the compromised regenerative response of the infarcted adult heart. Cardiovascular Regenerative Medicine 2017; 4: e1508. doi: 10.14800/crm.1508. http://www.smartscitech.com/index.php/crm.
Hertig V, Tardif K, Meus MA, Duquette N, Villeneuve L, Toussaint F, Ledoux J, Calderone A. Nestin expression is upregulated in the fibrotic rat heart and is localized in collagen-expressing mesenchymal cells and interstitial CD31(+)-cells. PLOS One, 12(4):e0176147, 2017.
Hertig V, Nieves AM, Garg V, Villeneuve L, Mamarbachi M, Caland L, Calderone A. Nestin expression is dynamically regulated in cardiomyocytes during embryogenesis. Journal of Cellular Physiology, 2018 Apr;233(4):3218-3229.
Calderone A. The biological role of nestin(+)-cells in physiological and pathological cardiovascular remodelling. Frontiers in Cell & Developmental Biology, 2018 (Accepted)