The effects of anti-VEGF and kinin B1 receptor blockade on retinal inflammation in laser-induced choroidal neovascularization.
Hachana S, Fontaine O, Sapieha P, Lesk M, Couture R, Vaucher E. Br J Pharmacol. 2020 May;177(9):1949-1966. doi:10.1111/bph.14962
Reciprocal Regulatory Interaction between TRPV1 and Kinin B1 Receptor in a Rat Neuropathic Pain Model.
Cernit V, Sénécal J, Othman R, Couture R. Int J Mol Sci. 2020 Jan 27;21(3):821. doi: 10.3390/ijms21030821.
Differential Expression of Kinin Receptors in Human Wet and Dry Age-Related Macular Degeneration Retinae.
Othman R, Berbari S, Vaucher E, Couture R. Pharmaceuticals (Basel). 2020 Jun 24;13(6):130. doi: 10.3390/ph13060130.
Diabetes-induced inflammation and vascular alterations in the Goto-Kakisaki rat retina.
Hachana S, Pouliot M, Couture R, Vaucher E. Curr Eye Res. 2020 Aug;45(8):965-974. doi: 10.1080/02713683.2020.1712730
Neuroligin-1 is altered in the hippocampus of Alzheimer’s disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers.
Dufort-Gervais J, Provost C, Charbonneau L, Norris C, Calon F, Mongrain V & Brouillette J (2020) Scientific Reports, 10:6956
Tau hyperphosphorylation induced by the anesthetic agent ketamine/xylazine involved the calmodulin-dependent protein kinase II.
Hector A, McAnulty C, Piché-Lemieux MÉ, Alves-Pires C, Buée-Scherrer V, Buée L & Brouillette J (2020) FASEB J, 34:2968-2977
A novel cationic N-type calcium channel inhibitor active against neurogenic inflammation.
Lee SK*, Jo S*, Talbot S, Puopolo M, Liu P, Jacquemont T, Lee J, Woolf CJ, and Bean BP.
eLife
Down-regulation of MHC class II by ubiquitination is required for the migration of CD206+ DCs to skin-draining lymph nodes.
Majdoubi A, Lee JS, Balood M, Sabourin A, DeMontigny A, Kishta OA, Moulefera M, Galbas T, Yun TJ, Talbot S, Ishido S, Cheong C, Thibodeau J.
Journal of Immunology. 2019. PMID: 31659013
Profiling of how nociceptor neurons detect danger; new and old foes.
Crosson T, Roversi K, Balood M, Othman R, Ahmadi M, Wang JC, Pereira PJS, Couture R, Latini AS, Prediger RDS, Rangachari M, Seehus CR, Foster SL, Talbot S.
Journal of Internal Medicine. 2019. PMID: 31282104
Neurons and microglia; a sickly-sweet duo in diabetic pain neuropathy.
Rajchgot T, Thomas S, Wang JC, Ahmadi M, Balood M, Crosson T, Dias JP, Couture R, Claing A and Talbot S.
Frontiers in Neuroscience. 2019. PMID: 30766472
Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.
Latini A, Couture R, Campos MM and Talbot S.
Oxidative Medicine and Cellular Longevity. 2019. PMID: 30723534
Dysregulation of ER stress response and calcium homeostasis in human iPSC-derived neurons carrying the LRRK2 G2019S mutation.
Korecka JA, Talbot S, Levy S, De Leeuw SM, Terpstra ML, Osborn TM, Hallett PJ, Jodelka FM, Woolf CJ, Hastings ML, Isacson O.
Stem Cell Report. 2019. PMID: 30595548
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Cronin SJF, Seehus CR, Weidinger A, Talbot S, Reissig S, Pierson Y, Longhi MS, McNeill E, Kreslavsky T, Kogler M, Seifert M, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Andrews N, Latremoliere A, Latini A, Lametschwandtner G, Busslinger M, Weiss G, Robson SC, Waisman A, Costigan M, Kozlov AV, Channon KM, Johnsson K, Woolf CJ, and Penninger JM.
Nature. 2018. PMID: 30405245
Sense and immunity: context-dependent neuro-immune interplay.
Foster SL, Seehus CR, Woolf CJ and Talbot S.
Frontiers in Immunology. 2017. PMID: 29163530.
The role of membrane-bound metal ions in toxicity of a human cancer cell-active pore-forming toxin Cry41Aa from Bacillus thuringiensis.
Domanska B, Fortea E, West MJ, Schwartz, JL, Crickmore N.
Toxicon. 2019 Jun 7;167:123-133. doi: 10.1016/j.toxicon.2019.06.003. PMID: 31181295
Cry6Aa1, a Bacillus thuringiensis nematocidal and insecticidal toxin, forms pores in planar lipid bilayers at extremely low concentrations and without the need of proteolytic processing.
Fortea E, Lemieux V, Potvin L, Chikwana V, Griffin S, Hey T, McCaskill D, Narva K, Tan SY, Xu X, Vachon V, Schwartz JL.
J Biol Chem. 2017 Aug 11;292(32):13122-13132. doi: 10.1074/jbc.M116.765941. PMID: 28623231
Bradykinin Type 1 Receptor – Inducible Nitric Oxide Synthase: A New Axis Implicated in Diabetic Retinopathy.
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Front Pharmacol. 2019 Mar 29;10:300. doi: 10.3389/fphar.2019.00300. eCollection 2019
Inhibition of overexpression of Giα proteins and nitroxidative stress contribute to sodium nitroprusside-induced attenuation of high blood pressure in SHR.
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Physiol Rep. 2018 Mar;6(6):e13658. doi: 10.14814/phy2.13658.
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Pharmacol Res Perspect. 2018 Feb;6(1). doi: 10.1002/prp2.375.
Natriuretic peptide receptor-C activation attenuates angiotensin II-induced enhanced oxidative stress and hyperproliferation of aortic vascular smooth muscle cells.
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Mol Cell Biochem. 2018 Nov;448(1-2):77-89. doi: 10.1007/s11010-018-3316-x. Epub 2018 Feb 7.
Nestin expression is dynamically regulated in cardiomyocytes during embryogenesis.
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The Biological Role of Nestin(+)-Cells in Physiological and Pathological Cardiovascular Remodeling.
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Front Cell Dev Biol. 2018 Feb 14;6:15. doi: 10.3389/fcell.2018.00015. eCollection 2018.
Dual functions of ARP101 in targeting membrane type-1 matrix metalloproteinase : Impact on brain cancer cell invasion and autophagy signaling.
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Chemical Biology & Drug Design, 2018 (sous presse)
Static Hand Posture Classification Based on the Biceps Brachii Muscle Synergy Features.
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J Electromyog and Kinesiol, doi: https://doi.org/10.1016/j.jelekin.2018.10.003, 2018
Phase singularity detection through phase map interpolation: Theory, advantages and limitations.
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Comput Biol Med. 2018 jul 24. Pii: S0010-4825(18)30205-1.
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Novel criterion for the differential diagnosis of wide QRS complexes and wide complex tachycardia using the initial activation of QRS on leads V1 and V2: Differential diagnosis of wide QRS based on V1-V2.
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Sense and immunity: context-dependent neuro-immune interplay.
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The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Cronin SJF, Seehus CR, Weidinger A, Talbot S, Reissig S, Pierson Y, Longhi MS, McNeill E, Kreslavsky T, Kogler M, Seifert M, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Andrews N, Latremoliere A, Latini A, Lametschwandtner G, Busslinger M, Weiss G, Robson SC, Waisman A, Costigan M, Kozlov AV, Channon KM, Johnsson K, Woolf CJ, Penninger JM.
Nature. 2018.
Microglia drives diabetic pain neuropathy.
Rajchgot T, Thomas S, Wang JC, Ahmadi M, Balood M, Crosson T, Dias JP, Couture R, Claing A and Talbot S*.
Frontiers in Neuroscience. Submitted. 2018/10/15. PIN: FTN1025-16
Dysregulation of ER stress response and calcium homeostasis in human iPSC-derived neurons carrying the LRRK2 G2019S mutation.
Korecka JA, Talbot S, Levy S, De Leeuw SM, Terpstra ML, Osborn TM, Hallett PJ, Jodelka FM, Woolf CJ, Hastings ML, Isacson O.
Stem Cell Report. In revision. October 2018. PIN: CSC-2310-17R2
Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration. Oxidative Medicine and Cellular Longevity.
Talbot S, Latini A, Couture R, Campos MM.
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Cardiotrophin-like Cytokine Increases Macrophage-Foam Cell Transition.
Pasquin S, Laplante V, Kouadri S, Milasan A, Mayer G, Tormo AJ, Savin V, Sharma M, Martel C, Gauchat JF.
J Immunol. 2018 Oct 15;201(8):2462-2471. doi: 10.4049/jimmunol.1800733. Epub 2018 Sep 12.
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Sci Rep. 2018 Mar 5;8(1):3990. doi: 10.1038/s41598-018-22400-y.
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J Neurochem. 2018 Mar;144(5):509-512. doi: 10.1111/jnc.14287. Epub 2018 Feb 11.
Differential effect of angiotensin II and blood pressure on hippocampal inflammation in mice.
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J Neuroinflammation. 2018 Feb 28;15(1):62. doi: 10.1186/s12974-018-1090-z.
Arterial stiffness induced by carotid calcification leads to cerebral gliosis mediated by oxidative stress.
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Comparative analysis of Parkinson’s disease-associated genes in mice reveals altered survival and bioenergetics of Parkin-deficient dopamine neurons.
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Histamine H3 Receptors Decrease Dopamine Release in the Ventral Striatum by Reducing the Activity of Striatal Cholinergic Interneurons.
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High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats.
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Psychopharmacology (Berl). 2018 Jan;235(1):317-328. doi: 10.1007/s00213-017-4773-8. Epub 2017 Oct 31.
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Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum.
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Br J Pharmacol. 2018 Mar;175(6):968-983. doi: 10.1111/bph.14138.
Periostin, a signal transduction intermediate in TGF-β-induced EMT in U-87MG human glioblastoma cells, and its inhibition by anthocyanidins.
Ouanouki A, Lamy S, Annabi B. (2018)
Oncotarget, 2018, 9 (31):22023-22037
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
Chennupati V, Veiga DF, Maslowski KM, Andina N, Tardivel A, Yu EC, Stilinovic M, Simillion C, Duchosal MA, Quadroni M, Roberts I, Sankaran VG, MacDonald HR, Fasel N, Angelillo-Scherrer A, Schneider P, Hoang T, Allam R.
J Clin Invest. 2018 Apr 2;128(4):1597-1614. doi: 10.1172/JCI94956. Epub 2018 Mar 19.
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Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Smith MJ, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M. Nat Commun. 2017 Oct 23;8(1):1099. doi: 10.1038/s41467-017-01326-5.
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Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylate Gab2 To Promote a Negative-Feedback Loop That Attenuates Phosphoinositide 3-Kinase/Akt Signaling.
Zhang X, Lavoie G, Méant A, Aubert L, Cargnello M, Haman A, Hoang T, Roux PP.
Mol Cell Biol. 2017 Mar 17;37(7). pii: e00357-16. doi: 10.1128/MCB.00357-16. Print 2017 Apr 1.
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The tyrosine phosphatase STEP is involved in age-related memory decline.
Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn A, Norris CM, Ferland G, Bézard E, Gaudreaud P, Lombroso P & Brouillette J (2018)
Current Biology; 28(7): 1079-1089
A three-way inter-molecular network accounts for the CaVα2δ1-induced functional modulation of the pore-forming CaV1.2 subunit.
Briot J, Mailhot O, Bourdin B, Tétreault MP, Najmanovich R, Parent L.
J Biol Chem. 2018 Mar 27. pii: jbc.RA118.001902. doi: 10.1074/jbc.RA118.001902.
Biophysical evidence for differential gallated green tea catechins binding to membrane type-1 matrix metalloproteinase and its interactors.
Djerir D, Iddir M, Bourgault S, Lamy S, ANNABI B (2018)
Biophysical Chemistry 234:34–41
High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats.
Allain F, Bouayad-Gervais K, Samaha AN.
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